Homeotherms, a.k.a. "warm-blooded" creatures, are those which naturally have the means to regulate their internal temperature, rather than depending on the environment.
Compared to poikilotherms (a.k.a. "cold-blooded" creatures), homeotherms are usually less vulnerable to extreme temperatures. However, they also spend significantly more energy, and need to feed more frequently.
On Earth, most animals are poikilotherms, with the main exception of birds and most mammals. There exist rare examples of cold-blooded mammals, though, such as the naked mole rat and the extinct goat Myotragus.
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